Cthrc1是什么
WebDec 7, 2012 · Collagen triple helix repeat containing-1 (CTHRC1) is a secreted protein involved in vascular remodeling, bone formation and developmental morphogenesis. CTHRC1 has recently been shown to be expressed in human cancers such as breast cancer and melanoma. In this study, we show that CTHRC1 is highly expressed in … WebPD-1(程序性死亡受体1),也称为CD279(分化簇279),是一种重要的免疫抑制分子。通过向下调节免疫系统对人体细胞的反应,以及通过抑制T细胞炎症活动来调节免疫系统并促进自身耐受。这可以预防自身免疫性疾病,但它也可以防止免疫系统杀死癌细胞。2024年12月,治疗霍奇金淋巴瘤的首个国产PD-1 ...
Cthrc1是什么
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WebOct 26, 2024 · Background: The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics methods represent a beneficial approach to examine the mechanism and function of the CTHRC1 gene in the disease process of cancers from a pan-cancer … WebCatalogue Number. MABT889. Description. Anti-CTHRC1 Antibody, clone Vli-55. Alternate Names. Collagen triple helix repeat-containing protein 1. Protein NMTC1. Background Information. Collagen triple helix repeat-containing protein 1 (UniProt Q96CG8; also known as Protein NMTC1) is encoded by the CTHRC1 gene (ORF UNQ762/PRO1550; Gene ID …
WebCTHRC1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTHRC1 INFORMATION. Proteini. Full gene name according to HGNC. Collagen triple … WebMar 20, 2024 · The collagen triple helix repeat containing 1 (CTHRC1) gene is located on human chromosome 8q22.3 and was initially identified in balloon injury and normal rat …
WebNational Center for Biotechnology Information WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt Pathway and Malignant pleural mesothelioma . Gene Ontology (GO) annotations related to this gene include frizzled binding and Wnt-protein …
WebSep 23, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) has been increasingly reported to be involved in tumorigenesis and/or tumor progression. However, limited data are available regarding the role of CTHRC1 in hepatocellular carcinoma. Methods: Paraffin-embedded specimens from a total of 29 patients with HCC were collected in our study. …
WebOct 24, 2016 · Epithelial ovarian cancer (EOC) is the major cause of deaths from gynecologic malignancies, and metastasis is the main cause of cancer related death. Collagen triple helix repeat containing-1 (CTHRC1) is a secreted protein that has the ability to inhibit collagen matrix synthesis. In this study, we found that high CTHRC1 … how to say walmart in japaneseWebJun 20, 2024 · Notably, CTHRC1 expression was significantly associated with macrophage infiltration, especially the immune infiltration gene marker set of M2. Copy number variations, DNA mutations and methylation states might be potential mechanisms for regulating CTHRC1 expression. Protein digestion and absorption, human papillomavirus infection, … how to say walkie talkie in frenchWebSep 30, 2016 · CTHRC1 (collagen triple-helix repeat-containing 1), a protein secreted during the tissue-repair process, is highly expressed in several malignant tumors, including pancreatic cancer. We recently ... north lincs bus timetablesWebNational Center for Biotechnology Information how to say walk in spanishWebCTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, mutation of the gene has been associated with carcinogenesis in a variety of cell and tissues, most notably esophageal adenocarcinoma and Barrett ... north lincs business ratesWebJul 22, 2014 · 癌和前列腺癌,CTHRC1 在多种实体肿瘤中广泛表第8 萍,等:CTHRC1与肿瘤关系的研究进展 799 达,并且可能与肿瘤组织侵袭转移有关。. 肿瘤的转 达后,细胞的迁移及侵袭 能力显著增强P0.001, [19] 移依赖于多种因素,包括肿瘤细胞侵入基质及穿透 说明该基因可能 … how to say wander in latinWebMar 20, 2024 · The collagen triple helix repeat containing 1 (CTHRC1) gene is located on human chromosome 8q22.3 and was initially identified in balloon injury and normal rat arteries . Its overexpression in fibroblasts is related to an increase in cell migration, motility and invasion . In adults, CTHRC1 is expressed only in the bone matrix and periosteum. north lincs camhs